New Step by Step Map For ceesdekker
New Step by Step Map For ceesdekker
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Spatial framework facilitates cooperation in a very social Problem: empirical proof from the bacterial Group
Our team reports bacterial cell division and is particularly aiming to constitute a ‘bottom up biology’ in artificial cells that can autonomously divide. Our primary desire lies in mobile division, chromatin framework, and spatial Handle.
, Groningen scientists present the results of their attempts to generate labs additional sustainable and supply guidelines for other labs.
Given that 2000, Dekker has shifted the most crucial target of his get the job done towards biophysics the place he experiments the properties of solitary biomolecules and cells utilizing the applications of nanotechnology. This transformation of discipline was pushed by his fascination for the exceptional operating of Organic molecular buildings, in addition to because of the long-phrase point of view that numerous fascinating discoveries could be predicted With this industry.[5] Present traces of exploration in his biophysics team are during the parts of:[six]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initial at any time examine with the dynamics DNA supercoils and the invention of supercoil hopping
Immediate immobilization of indigenous yeast iso-1 cytochrome c on bare gold: rapid electron relay to redox enzymes and zeptomole protein-film voltammetry
You're a Christian. If you might make such a artificial cell, would you be one action closer to God, or would the purpose of God have diminished considerably again?
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Comprehending basic processes regulating the spatial and dynamic organisation from the DNA in Reside cells.
‘The fantastically delicate way where factors in character operate never ever ceases to amaze me. If we remedy the puzzle of how existence came into being, I hope that my amazement for the complexity of development can have greater and with it my awe for that greatness on the Creator.’
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Cees Dekker is Distinguished College Professor at TU Delft. Qualified being a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineties. Due to the fact 2000, he moved to solitary-molecule biophysics and nanobiology. His recent investigation focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is surely an elected member from the KNAW and fellow towards the APS and also the IOP.
2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin in the electrophoretic power on DNA in nanopores; identified a substantial velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in purple, along with a 3D rendering with ceesdekker the motion on the DNA rod is displayed.